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TB: |
mycobacterium tuberculosis |
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MDR-TB: |
multidrug-resistant TB |
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XDR-TB: |
extensively drug-resistant TB |
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TdP: |
Torsades de Pointes |
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ECG: |
electrocardiogram |
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QT interval: |
time between Q wave onset and T wave end in the ECG |
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APD: |
action potential duration |
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SR: |
sarcoplasmic reticulum |
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sub-SL: |
nonjunctional subsarcolemmal compartment |
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CICR: |
calcium induced calcium release |
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IKr: |
rapid component of the delayed rectifier potassium current |
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IKs: |
slow component of the delayed rectifier potassium current |
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HH: |
Hodgkin-Huxley |
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INa: |
fast sodium current |
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IK1: |
inward rectifier potassium current |
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ICaL: |
L type calcium current |
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Ito: |
transient outward potassium current |
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Itof: |
fast component of the transient outward potassium current |
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Itos: |
slow component of the transient outward potassium current |
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INaCa: |
sodium-calcium exchange current |
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INaK: |
sodium-potassium pump current |
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JSRrel: |
SR calcium release flux |
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JSRleak: |
SR calcium leak flux |
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JSRpump: |
SR calcium pump flux |
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INaBk: |
background sodium leak current |
• |
ICl(Ca): |
calcium dependent chloride current |
• |
IClBk: |
background chloride current |
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IKp: |
plateau potassium current |
• |
ICaP: |
sarcolemmal calcium pump current |
• |
ICaBk: |
background calcium current |