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Editors: Mayuri S. Prasad, Aalborg University, DenmarkPaolo Di Nardo, University of Tor Vergata, Italy
ISBN: 9788793237094
e-ISBN: 9788793237100
doi: https://doi.org/10.13052/rp-9788793237100
Price: €0.00
Available: January 2015
Print book available at List Price
Description:
In spite of intensive investments and investigations carried out in the last decade, many aspects of the stem cell physiology, technology and regulation remain to be fully defined. After the enthusiasm that characterized the first decade of the discovery that when given the right cue, stem cells could repair all the different tissues in the body; it is now time to start a serious and coordinated action to define how to govern the stem cell potential and to exploit it for clinical applications. This can be achieved only with shared research programs involving investigators from all over the world and making the results available to all. The Disputationes Workshop series (http://disputationes.info) is an international initiative aimed at disseminating stem cell related cutting edge knowledge among scientists, healthcare workers, students and policy makers. The present book gathers together some of the ideas discussed during the third and fourth Disputationes Workshops held in Florence (Italy) and Aalborg (Denmark), respectively. The aim of this book is to preserve those ideas in order to contribute to the general discussion on organ repair and to bolster a fundamental scientific and technological leap forwards the treatment of otherwise incurable diseases.
Keywords:
Nanocomposites, iPSC, derivation strategies, cerium dioxide, cardiac precursor cells, hydrogels, ESCs, spermatogonial stem cells, regulatory issues, medical devices, flexible modular platform, automation, cell sheet, animal models, biomaterial development, MSCs, neural disorders, mechanical stimulation, melenoma stem cells, hedgehog signalling
Book Contents:
Chapter 1 Bioactive Nanocomposites with Applications in Biomedicineby C.-G. Sanporean, Z. Vuluga, J.deC. Christiansen Download as a PDF [6052KB]
Chapter 2 Cerium Dioxide Nanoparticles Protect Cardiac Progenitor Cells against the Oxidative Stressby Francesca Pagliari, Giorgia Nardone, Enrico Traversa and Paolo Di Nardo Download as a PDF [1237KB]
Chapter 3 Animals Models and In Vitro Alternatives in Regenerative Medicine: Focus on Biomaterials Developmentby Monika Kozak Ljunggren, DVM, PhD and May Griffith, PhD Download as a PDF [2135KB]
Chapter 4 Differentiation Plasticity of Germline Cell-Derived Pluripotent Stem Cells and Their Potential Application in Regenerative Medicineby Sharmila Fagoonee, Letizia De Chiara, Lorenzo Silengo and Fiorella Altruda Download as a PDF [72KB]
Chapter 5 Mechanical Stimulation in Tissue Engineeringby John Rasmussen, Cristian Pablo Pennisi, Tea Rasmussen, Marcelo Ferreira, Christian Gammelgaard Olesen and Vladimir Zachar Download as a PDF [2098KB]
Chapter 6 Immune Properties of Mesenchymal Stem Cells in the Translation of Neural Disordersby Garima Sinha, Sarah A. Bliss, Vipul Nagula, Lauren S. Sherman, Pranela Rameshwar Download as a PDF [402KB]
Chapter 7 Novel Design of Manufacturing Bioreactor and Facility of Cell-Based Health Care Products for Regenerative Medicineby Masahiro Kino-oka Download as a PDF [1310KB]
Chapter 8 Insight into Melanoma Stem Cells:The Role of the Hedgehog Signaling in Regulating Self-Renewal and Tumorigenicityby Barbara Stecca and Roberta Santini Download as a PDF [458KB]
Chapter 9 A Quest for Refocussing Stem Cell Induction Strategies: How to Deal with Ethical Objections and Patenting Problemsby Hans-Werner Denker Download as a PDF [386KB]
Chapter 10 Constitutive Equations in Finite Viscoplasticity of Nanocomposite Hydrogelsby A.D. Drozdov, and J. deClaville Christiansen Download as a PDF [204KB]
Chapter 11 Regulatory Issues in Developing Advanced Therapy Medicinal Products with Stem Cells in Europeby Maria Cristina Galli, B.Sc., Ph.D. Download as a PDF [55KB]