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River Publishers Series in Biotechnology and Medical Research 

Innovative Strategies in Tissue Engineering

Mayuri S. Prasad, Aalborg University, Denmark
Paolo Di Nardo, University of Tor Vergata, Italy

ISBN: 9788793237094

e-ISBN: 9788793237100

doi: https://doi.org/10.13052/rp-9788793237100

Price: €0.00

Available: January 2015

Print book available at List Price

[17.7 MB] Downloads: [714] Reads [462]    


In spite of intensive investments and investigations carried out in the last decade, many aspects of the stem cell physiology, technology and regulation remain to be fully defined. After the enthusiasm that characterized the first decade of the discovery that when given the right cue, stem cells could repair all the different tissues in the body; it is now time to start a serious and coordinated action to define how to govern the stem cell potential and to exploit it for clinical applications. This can be achieved only with shared research programs involving investigators from all over the world and making the results available to all.

The Disputationes Workshop series (http://disputationes.info) is an international initiative aimed at disseminating stem cell related cutting edge knowledge among scientists, healthcare workers, students and policy makers. The present book gathers together some of the ideas discussed during the third and fourth Disputationes Workshops held in Florence (Italy) and Aalborg (Denmark), respectively. The aim of this book is to preserve those ideas in order to contribute to the general discussion on organ repair and to bolster a fundamental scientific and technological leap forwards the treatment of otherwise incurable diseases.



Nanocomposites, iPSC, derivation strategies, cerium dioxide, cardiac precursor cells, hydrogels, ESCs, spermatogonial stem cells, regulatory issues, medical devices, flexible modular platform, automation, cell sheet, animal models, biomaterial development, MSCs, neural disorders, mechanical stimulation, melenoma stem cells, hedgehog signalling

Book Contents:

Chapter 1
Bioactive Nanocomposites with Applications in Biomedicine
by C.-G. Sanporean, Z. Vuluga, J.deC. Christiansen
Download as a PDF [6052KB]

Chapter 2
Cerium Dioxide Nanoparticles Protect Cardiac Progenitor Cells against the Oxidative Stress
by Francesca Pagliari, Giorgia Nardone, Enrico Traversa and Paolo Di Nardo
Download as a PDF [1237KB]

Chapter 3
Animals Models and In Vitro Alternatives in Regenerative Medicine: Focus on Biomaterials Development
by Monika Kozak Ljunggren, DVM, PhD and May Griffith, PhD
Download as a PDF [2135KB]

Chapter 4
Differentiation Plasticity of Germline Cell-Derived Pluripotent Stem Cells and Their Potential Application in Regenerative Medicine
by Sharmila Fagoonee, Letizia De Chiara, Lorenzo Silengo and Fiorella Altruda
Download as a PDF [72KB]

Chapter 5
Mechanical Stimulation in Tissue Engineering
by John Rasmussen, Cristian Pablo Pennisi, Tea Rasmussen, Marcelo Ferreira, Christian Gammelgaard Olesen and Vladimir Zachar
Download as a PDF [2098KB]

Chapter 6
Immune Properties of Mesenchymal Stem Cells in the Translation of Neural Disorders
by Garima Sinha, Sarah A. Bliss, Vipul Nagula, Lauren S. Sherman, Pranela Rameshwar
Download as a PDF [402KB]

Chapter 7
Novel Design of Manufacturing Bioreactor and Facility of Cell-Based Health Care Products for Regenerative Medicine
by Masahiro Kino-oka
Download as a PDF [1310KB]

Chapter 8
Insight into Melanoma Stem Cells:The Role of the Hedgehog Signaling in Regulating Self-Renewal and Tumorigenicity
by Barbara Stecca and Roberta Santini
Download as a PDF [458KB]

Chapter 9
A Quest for Refocussing Stem Cell Induction Strategies: How to Deal with Ethical Objections and Patenting Problems
by Hans-Werner Denker
Download as a PDF [386KB]

Chapter 10
Constitutive Equations in Finite Viscoplasticity of Nanocomposite Hydrogels
by A.D. Drozdov, and J. deClaville Christiansen
Download as a PDF [204KB]

Chapter 11
Regulatory Issues in Developing Advanced Therapy Medicinal Products with Stem Cells in Europe
by Maria Cristina Galli, B.Sc., Ph.D.
Download as a PDF [55KB]


Innovative Strategies in Tissue Engineering