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The Application of a New Tool for Evaluation of Lung Function in COPD

Author: Lars Pilegaard Thomsen, Center for Model-Based Medical Decision Support, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark


e-ISBN: 9788793102415

doi: https://doi.org/10.13052/rp-9788793102415

Price: Notify Me

Available: December 2013
Downloads: [1891]

Downloads: [1891]  
Technical | Layman

Layman Description:

The diagnosis and classification of COPD can be seen as the difficult task of describing a heterogeneous disease affecting a complex organ, using relatively simple measurements. Combining these simple measurements can aid in describing the impact of disease on the lung and its functional capacity can provide additional information enabling the clinician to succeed in this task. In this context, this thesis has investigated the clinical description of pulmonary gas exchange abnormalities, including the current standard, the state-of-the-art experimental techniques and a new alternative named ALPE.

This thesis has demonstrated that ALPE may possibly be used as a tool for functional description in patients suffering from COPD. A developed causal network integrating ALPE with other routinely available measurements, may be used to target radiologic phenotypes of COPD, possibly in long-term clinical cohort studies or in daily clinical practice.


Keywords:

diagnosis and classification